LL-37 is the only human cathelicidin peptide, investigated for direct antimicrobial activity, innate immune modulation, wound healing, anti-biofilm properties, and cancer biology research.
| Molecular Weight | 4493.3 g/mol |
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
LL-37 is the only human antimicrobial peptide (AMP) belonging to the cathelicidin family. It is a 37-amino acid peptide that plays a critical role in the innate immune system, acting as a first line of defense against pathogens.
LL-37 works through multiple pathways. It can directly destroy bacteria by disrupting their cell membranes and also acts as a potent signaling molecule (alarmin). It recruits immune cells to the site of infection and modulates the inflammatory response to prevent tissue damage.
Research indicates that LL-37 is essential for proper wound healing. It stimulates the migration of skin cells (keratinocytes) and promotes angiogenesis (the growth of new blood vessels). It is currently a major subject for studies on chronic non-healing wounds and the treatment of antibiotic-resistant infections.