Melatonin is the primary pineal gland hormone investigated for circadian rhythm regulation, antioxidant defense, immune modulation, and neuroprotective pathway research.
| Molecular Weight | 232.28 g/mol |
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
Melatonin is a naturally occurring hormone produced primarily by the pineal gland. It is the master regulator of the circadian rhythm (the body's internal clock) and is found in nearly all living organisms, from bacteria to humans.
Melatonin works by binding to two specific G protein-coupled receptors, MT1 and MT2. These receptors are distributed throughout the brain and body. By activating these receptors, melatonin signals the body that it is time to transition to a physiological state of rest and repair. It also acts as a powerful direct free radical scavenger.
Beyond sleep, Melatonin is heavily researched for its neuroprotective properties. It can cross the blood-brain barrier and protect neurons from oxidative stress and neuro-inflammation. Laboratory studies also investigate its role in mitochondrial health, immune system modulation, and its potential oncostatic (cancer-inhibiting) effects in specific research models.