IGF-1 LR3 is a long-chain analogue of insulin-like growth factor-1 engineered to resist IGF-binding proteins. It is studied for cellular growth, muscle hypertrophy, and protein synthesis research.
| Molecular Weight | 9200 g/mol |
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
IGF-1 LR3 (Long Arginine 3-IGF-1) is a synthetic, 83-amino acid analogue of human Insulin-like Growth Factor-1. It is modified to include a 13-amino acid extension and a substitution at the third position, which makes it 2-3 times more potent than standard IGF-1.
The primary advantage of IGF-1 LR3 is its resistance to IGF-binding proteins (IGFBPs). Normally, IGFBPs neutralize IGF-1 in the blood. By avoiding these proteins, IGF-1 LR3 stays active in the body for up to 20-30 hours, compared to only 20 minutes for natural IGF-1.
Research indicates that IGF-1 LR3 is the most potent peptide for inducing muscle hyperplasia (the creation of new muscle cells) rather than just hypertrophy (the enlargement of existing cells). It is a primary subject for studies on muscle wasting, tissue repair, and the activation of satellite cells for systemic growth.