SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that concentrates in the inner mitochondrial membrane, investigated for cardioprotection, oxidative stress reduction, and mitochondrial function research.
| Molecular Weight | 639.80 g/mol |
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
SS-31 (also known as Elamipretide) is a synthetic tetrapeptide that belongs to the Szeto-Schiller (SS) family. It is a highly specialized molecule designed to selectively target and concentrate within the inner mitochondrial membrane.
SS-31 works by binding to cardiolipin, a unique phospholipid found only in the inner mitochondrial membrane. Cardiolipin is essential for the structural integrity of the mitochondria and the function of the electron transport chain. By stabilizing cardiolipin, SS-31 prevents mitochondrial pore formation, reduces oxidative stress, and optimizes energy production.
Research into SS-31 is primarily focused on its powerful cardioprotective effects. It is studied for its ability to treat heart failure, improve renal function, and protect the heart from ischemia-reperfusion injury. It is a major subject for studies on mitochondrial dysfunction and the treatment of rare mitochondrial diseases.