SLU-PP-332 is a synthetic ERRα/γ agonist investigated as an exercise mimetic for mitochondrial biogenesis, oxidative metabolism, and muscle endurance research.
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
SLU-PP-332 is a synthetic small molecule that acts as a potent agonist of Estrogen-Related Receptors (ERR), specifically alpha, beta, and gamma. It is widely considered the most effective "exercise mimetic" discovered to date.
SLU-PP-332 works by activating the ERR receptors, which are the primary regulators of mitochondrial biogenesis and oxidative metabolism. This triggers a biological cascade that "tricks" muscle fibers into thinking they have undergone intense aerobic exercise, leading to increased mitochondrial density and fatty acid oxidation.
Research indicates that SLU-PP-332 can significantly increase running endurance and muscle strength in animal models without any actual training. It is being studied for its potential to treat muscle wasting (sarcopenia), obesity, and heart failure by improving the energy efficiency of skeletal and cardiac muscle.