Kisspeptin-10 is the C-terminal decapeptide of kisspeptin, a GPR54 receptor agonist investigated for GnRH pulse regulation, LH and FSH secretion, puberty, and reproductive endocrinology research.
| Molecular Weight | 1302.5 g/mol |
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
Kisspeptin-10 is a synthetic decapeptide (10 amino acids) that represents the most biologically active fragment of the natural kisspeptin protein. It is the "master switch" for the initiation of the reproductive axis in all mammals.
Kisspeptin-10 works by binding to the GPR54 (KISS1R) receptor on neurons in the hypothalamus. This triggers the release of Gonadotropin-Releasing Hormone (GnRH), which then signals the pituitary to produce LH and FSH. It is the primary signal that tells the body to begin or maintain reproductive function.
Research into Kisspeptin-10 focuses on its potential to treat hypothalamic amenorrhea, restore fertility, and modulate testosterone levels. Unlike direct GnRH agonists, Kisspeptin provides a more physiological way to stimulate the HPG axis, making it a critical subject for endocrinology and oncology research.