Ipamorelin is a selective GH secretagogue receptor agonist investigated for pulsatile GH release, body composition, and endocrine axis research.
| Molecular Weight | 711.85 g/mol |
| Purity | >98% |
| Form | Lyophilized powder |
| Storage | -20°C |
Science-backed research overview for this compound
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts as a potent and selective secretagogue of Growth Hormone. It is often cited as the mildest and most stable GHRP available for clinical research.
Ipamorelin works by mimicking ghrelin and binding to the Growth Hormone Secretagogue Receptor (GHSR). However, unlike GHRP-2 or GHRP-6, it is highly selective for GH release and does not significantly increase levels of cortisol, prolactin, or appetite-stimulating hormones.
Laboratory studies show that Ipamorelin promotes a clean, pulsatile release of GH that supports fat loss, muscle growth, and bone density without the side effects of older GHRPs. It is a primary choice for researchers studying healthy aging and long-term metabolic health.